Bulk 8-Hydroxyhexahydrocannabinol (8-OH-HHC Distillate)

Hemp-derived 8α-hydroxy-hexahydrocannabinol (8α-OH-HHC) and 8β-hydroxy-hexahydrocannabinol (8β-OH-HHC) are two naturally occurring metabolites of hexahydrocannabinol (HHC). They are typically generated in the highest concentrations during the ‘first pass’ metabolism following oral consumption. The physical characteristics of hemp-derived 8-OH-HHC distillate are distinctive, making it easier to manage compared to other hemp derivatives. To ensure optimal shelf life, it is advised to store the material properly in a cold, inert, and light-protected environment.The physical properties of hemp-derived 8-OH-HHC distillate are distinct, making it simpler to handle compared to other hemp derivatives. This clear amber glass-like substance is a non-crystalline solid that quickly liquefies between 80°C and 90°C or slightly higher. It remains stable at room temperature and can be molded into shapes or sheets without significant puddling or deformation upon cooling. Even when diluted at 20-30% diluent concentrations, which produce a viscous liquid, 8-OH does not crystallize, maintaining its solid form.
Our Hemp derived 8-OH-HHC is made from CBD that has been hydrogenated into HHC . There are no double bonds in the cyclohexyl ring like D8/D9 have – they have been removed from the structure and hydrogen’s have been added to the compound. Hydrogenation usually depends on scarce transition metal catalysts such as palladium, platinum, rhodium, ruthenium, iridium, and nickel. Oxidizing agents like selenium, osmium, ruthenium, chromium, manganese, molybdenum, or halogens many of these materials are often carcinogenic and can be even more dangerous. These methods frequently employ harsh industrial solvents, which may contaminate the end products and produce persistent waste streams that create a continuous environmental impact. Our 8-OH-HHC is made using technology and processes that are free of transition metals, utilize eco-friendly, biodegradable, plant-based solvents that do not contaminate water sources, harm the ozone layer, or contribute to air pollution.

Hemp derived 8-OH-HHC is versatile in how it can be consumed. It can be ingested orally, applied topically, or inhaled through vaporization, making it a flexible and versatile compound.

Properties:

• Pure 8-OH-HHC (94.88% purity)
• Chromatogram Available under our lab results section
• 37.440607% Beta-8-OH-HHC
• 57.433972% Alpha-8-OH-HHC
• Solid amber crystalline material at room temperature

Scientists have discovered over 100 metabolites of Δ9-THC, with some possessing psychotropic properties. The metabolism of cannabinoids is highly intricate, involving a diverse detoxification process that adds various functional groups at multiple positions on the carbon backbone.

Upon consumption, cannabinoids are primarily metabolized in the liver by cytochrome P450 enzymes (CYP2C9, CYP2C19, and CYP3A4 isozymes). In the primary metabolism stage, liver enzymes oxygenate cannabinoids to facilitate their excretion. Some metabolites exhibit psychoactive properties and are believed to subtly contribute to the parent molecule’s psychotropic effect.

C8 oxygenation plays a significant role in Δ9-THC metabolism, leading to the production of 8α- and 8β-OH-THC. Studies indicate that HHC, a naturally occurring cannabinoid and a possible product of THC metabolism, follows a similar oxygenation pathway to THC. The conversion of HHC to 8α- and 8β-OH-HHC varies depending on the species studied.